Archive for the ‘Scientific Culture’ Category

The Pope of Orgo at Harvard

Wednesday, March 13th, 2013

Is anyone else loving this papal conclave?  It’s so refreshing to hear people actually speaking Latin. The constant parade of cardinals in the news just brought to mind a quick story from grad school:

At a weekly meeting of teaching assistants, one of the profs I taught for told us about a professor who came to the department as a visitor to teach sophomore organic chemistry. On the first day of the semester, he introduced the course’s teaching assistants and finished by saying that he was the pope, the TAs were his cardinals, and you never go directly to the pope.

As with the infamous Guido letter, it is always interesting to hear of a professor embracing his villainy. Habemus jerkface.

Professor Baran Enters the Blogosphere

Tuesday, March 5th, 2013

First they ignore you,
then they laugh at you,
then they fight you,
then they join you,
then everybody wins.

Mahatma Gandhi posted that piece of advice on his blog shortly before his death in 1948, and it still holds true today.

After admitting that chemistry faculty typically roll their eyes at blogs and that he personally doesn’t have time for them, Phil Baran—or, more precisely, the Baran Lab at Scripps—has established the newest chemistry blog on the Internet. Baran and his lab are at the top of the game of organic synthesis, so this is a major development for academic chemistry. Their participation can do nothing but lend legitimacy to an activity that has been robustly and repeatedly poo-pooed by the respected Old School of our field.

The establishment of the Baran Lab’s blog fell out of the ongoing post-publication review of IBX-promoted benzylic oxidation at Blog Syn, a relatively new site that focuses on checking synthetic procedures in the vein of Organic Syntheses. Post-publication peer review is something familiar to the chemical blogopshere. Previous examples include the questioning of the science in the “Arsenic Life” paper, the exposure of duplication by Breslow in the “Space Dinosaur” saga, and the experimental investigation into the oxidation-by-NaH paper in JACS. Blog Syn takes post-publication review of synthetic procedures to the next level by coordinating replication of the procedures among a group of bloggers who compile and compare their results for all to see and discuss.

Last month, Blog Syn decided to examine a method for IBX-promoted benzylic oxidation published as part of Baran’s graduate work in K.C. Nicolaou’s lab. What started as a straightforward effort to test the (questioned) reproducibility of the reaction quickly evolved into a vigorous and thoughtful discussion of both the merits of anonymous bloggers’ questioning peer-reviewed research and of the reaction itself. Baran and the first author of the paper have participated actively in the generation of data and its analysis, and the most recent development appears to be improved mechanistic insight as to how the reaction might work.

Those interested in this specific reaction can check out the discussion for themselves, but all chemists can appreciate the value that blogs and other Web 2.0 venues offer in terms of advancing scientific knowledge and enriching our understanding of chemistry. While blogs may often engage in journalism that is a little rough at the edges, the ease of online publishing has helped to provide open venues for meaningful discussion, to give voice to important ideas, and to democratize power in a field where many grumble that power is overly centralized. What Blog Syn has started is a great service to the field of organic chemistry, and I look forward to the wealth of material that the Baran Lab can bring to the table in its own addition to the blogosphere.

Great stuff!

Edit to add: This great post by Rich Apodaca at Depth First places Blog Syn in historical context among similar experiment-based efforts in the chemical blogosphere. The post also offers an interesting analysis of the role that blogger anonymity plays.

Edit: Another (similar) great analysis and comment thread in this post by DrFreddy at C&EN‘s blog.

Combatting Chemophobia

Friday, February 1st, 2013

Chemical Ed with GogglesThe annual ScienceOnline 2013 conference is taking place in North Carolina, and chembloggers Carmen Drahl and Dr. Rubidium are running a session tomorrow on chemophobia. You can follow updates on Twitter labeled with the hashtag #chemophobia.

Personally, I think the greatest failure of our field over the past three decades has been the steady decline of the public image of chemistry. Our “brand” has steadily deteriorated from an apex of “better living through chemistry” in the 1970s to the ever-worsening current climate where “chemicals are bad” and products are nonsensically advertized as “chemical-free”.

There certainly are cases where specific chemists and chemicals have had horrific consequences for the public (e.g., thalidomide or the Bhopal disaster), but surely these cases are balanced by the numerous ways that chemistry has improved modern life: from countless new pharmaceuticals that improve health to a wide array of new materials that make modern technology possible. That’s all “chemistry” and “chemicals”, but the average person-on-the-street would probably not associate these advances with our science.

Of course, this is a blog for chemists, so there’s no sense wasting time here celebrating all of the benefits of chemicals and chemistry. Rather, why don’t we focus on how utterly stupid our field is with regard to communicating these benefits? Despite the manifestly dire state of the public image of chemistry, chemists continue to do nothing to correct the problem.

But, Paul…is it really a problem? Who cares if the public dislikes chemicals? So long as chemists know better, we will continue doing good science. Why should we be distracted by general ignorance?

The problem with that argument is that we live in a democracy. For a democracy—where the People govern by voting—to function efficiently, the electorate must be educated and informed. The steady decline of chemistry’s public image is a massive problem, because it erodes support for our field. Taxpayers fund our research, and if they are convinced that not only is chemistry not helping the world, it is hurting it, then what is going to stop politicians from cutting funding? This is already occurring. Look at how many Americans vilify scientists who support the highly (un)controversial theory of evolution. We also spend many, many times more money on the DoD than scientific research because the public is generally much more concerned about the threat of foreign dictators than the combined threats of insidious disease and the global energy crisis. Seem stupid? Well, turn on the news tonight. What are people talking about, the Middle East or cancer? And what’s worse than people not knowing anything about chemistry is when they “know” incorrect negative information about chemistry. That’s basically where we are.

Hey Paul, isn’t this something the ACS should handle?

Yes! Actually, it is something all of us should take responsibility for handling to some degree, but the ACS should be at the forefront. This brings me to the point: WHAT THE HELL HAS THE ACS BEEN DOING FOR THE PAST 30 YEARS? As far as I can tell, very little in the public-image battle, and the miserable status quo is all the evidence you need that our professional society has failed its mission in this regard.

OK, wise guy, what should the ACS be doing?

I can think of a number of things, but let me give you two: one from the executive level and one from the grass-roots level. First, the ACS needs to get a handle on misinformation in the media. When someone blurts “chemical-free” into a microphone or opines about the hazards of a compound with zero supporting evidence, the ACS should have someone step up and provide a rebuttal. We need a “war room” at ACS headquarters that monitors all major media outlets and contacts editors and producers when something is wrong. The war room should have experts trained in public communication who are camera-ready 24 hours a day and a TV studio on-site for satellite interviews. Reporters are getting lazier; we must adapt. At the grass-roots level, the ACS needs to do a better job organizing outreach efforts and coordinating volunteer chemists to run these programs. More on that below.

Whoa. Volunteer chemists and outreach programs? What are you talking about?

I think it is important that every chemist spend some time engaging the general public for the purposes of education and promoting the benefits of our field. Let me toss out a ball-park figure: 5% of your time allotted to chemistry.

You want me doing what, exactly?

Pretty much anything where you are bringing science/chemistry to a population not already intimately involved in the field. I am not talking about writing essays for Angewandte or leaving comments on In the Pipeline. I am talking about: (1) judging kids’ science fairs, (2) writing letters to the editors of newspapers to correct misinformation, (3) running or volunteering at a local science club, (4) explaining your research at a science cafe, (5) volunteering to talk to a middle-school science class, (6) developing a lab exercise for high schoolers based on your research, (7) making a science Web site for a general audience, (8) making YouTube videos pretending you are “Phil Nye the Chemistry Guy”, (9) editing Wikipedia, (10)…   need I go on? Anything. Anything! There are thousands of possibilities. If you don’t think you have a good idea, other people should have plenty of ideas in need of volunteers.

You think this will work?

Yes. I believe it will help. I think that education and outreach, or “E & O” in NASA parlance, is exactly what kept a largely overpriced set of shuttle missions in operation for so long. Spacemen realize that they need the public on their side, so they appeal to the public. I assume astronauts on space stations have more important scientific activities they could be doing than giving interviews to the yentas on The View, but NASA has the big picture in mind. If NASA could keep the space shuttles up so long, think about all of the additional funding we could bring to a field of science that is much more successful at improving people’s lives.

What’s in it for me?

Lots of things: (1) you’ll become better at communicating and teaching technical material, (2) you’ll feel good having taught someone something, (3) you’ll be giving back to society – was there a role-model or teacher when you were young that made you want to pursue a career in science?, (4) you are making the world less dumb, one person at a time, (5) in thinking about fundamental concepts and how to explain/teach them, you will invariably come up with new ideas. Sometimes it’s nice to think about areas of chemistry outside your focus of research, (6) you will help to improve the funding climate by persuading voters chemistry is valuable.

Bah. Those are worthless. I can’t list those on my CV!

Actually, you can list outreach activities on your CV. They may even make you seem human, you robotic hardass.

Seriously, my boss/advisor won’t care. Actually, I’ll get in trouble because he views them as a waste of time.

Public engagement should be a shared responsibility. Perhaps the reason almost nobody pitches in is because “why should I do it if the guy over there doesn’t?”  We need to find ways to incentivize desired behavior. Maybe a small outreach component for Ph.D. theses? Maybe make it part of tenure packages?

But Paul, I went through 11 years of university training to become a high-powered research machine. I am God’s gift to chemical research. I can think of nothing more inefficient than removing me from the bench to muck around with third-graders. Can’t we just hire professional outreach people so I can be left alone?

First, you are going to be able to bring things to the table that an education professional would not. Second, if you are truly “God’s gift to chemical research”, then you are a rock star. People love rock stars of any field. That is why we are willing to watch events like curling in the Olympics. You will be a great help! Also, get over yourself! Astronauts frequently give interviews while working in space. I assume there are probably some experiments they could be doing, but NASA recognizes the importance of education and interacting with the public.

Paul, I am too busy, go away.

What if everyone were too busy? Everyone is too busy! You can make a little time for this. C’mon.

Paul, I am still unconvinced this is actually worth my time.

Fine. You are a selfish jackass. I hope there are enough good chemists out there who can make up for your dereliction.

 

Folks, if we don’t start getting serious about addressing chemophobia, we are going to find ourselves in a bad, bad place as a profession, and the consequences for mankind won’t be pretty either.

Columbia Professor Dance Party

Saturday, December 15th, 2012

This video is pretty hilarious:

Congrats to Breslow, Nakanishi, and Sames for having good senses of humor. The holiday skits at Harvard were canceled a long time ago because a few people there took themselves a little too seriously.

Also, thanks to the three tipsters who e-mailed me different versions of this link. (And, of course, now that I’ve gone back and checked, this video has already made the rounds on Twitter. I will now go back under my rock. Bye.)

ChemBark’s First Poll. Ever.

Wednesday, September 26th, 2012

 

Would you join an upstart professional organization of chemists dedicated to advancing the public image of chemistry, providing inexpensive access to scholarly journals, and effecting meaningful change in the ACS through winning ACS elections?

 


 

 

Did Sheri Sangji Die in Vain?

Saturday, August 4th, 2012

I was away last week, and I’m still processing all of the recent developments in the Patrick Harran case. Harran, a chemistry professor at UCLA, is facing three felony charges in the wake of the death of Sheri Sangji in a lab accident involving t-butyllithum. Last week, the Los Angeles district attorney dropped charges against UCLA in exchange for its acceptance of responsibility for the safety conditions in the Harran lab and the establishment of an improved safety program. The agreement does not immediately affect the case against Harran, whose legal team filed a seperate motion to quash the charges against him because the state safety investigator allegedly committed murder as a juvenile (WTF?!). The court will rule on the motion next month.

I started drafting this post by jotting down a list of thoughts on the case, but they were too muddled to be of value. The situation is a mess, and what trumps my frustration in our legal system is my frustration in the culture of our profession.

You’d have hoped that the academic community would have straightened up in the wake of such a tragic accident. The circumstances of how Sangji died are horrifying: the fire covered 50% of her body in burns; the flesh in her hands burned off leaving exposed tendons; her abdominal wall was destroyed; she took 18 agonizing days to die. It was brutal:

If you watch that video, produced by California Watch and The Center for Public Integrity, you’ll find this statement from Jim Kaufman of The Laboratory Safety Institute:

This was a tsunami throughout academia that criminal charges were being filed against the university. I think that good things are going to come as a result of this and that Sheri Sangji’s death will not be in vain.

Allow me to preface my next statement by apologizing to the Sangji family for my lack of tact, but I am afraid that Sheri did die in vain. Harran can be punished to the fullest extent of the law and UCLA can throw all sorts of money at safety initiatives, but those actions are not solutions to the underlying problem here. The most important issue is that thousands of young, inexperienced researchers in university labs are performing chemical research with a gross lack of understanding of the hazards of their work. And, to me, it appears that the Sangji story has done little to change that.

Earlier this week, I took an informal survey of some of my colleagues by posing the following question:

t-butyllithium reacts violently with air. The guy in the hood next to you spills a solution of it on himself and catches on fire. What should you do?

The majority of people I asked responded they should find a fire blanket and smother the flames. (Recall, this is roughly what the first labmate to treat Sangji did.) If a person said to “use the safety shower”, in about half of cases I could knock them off this (correct) idea by saying “but tBuLi reacts violently with water.” Just a couple of people had the confidence to insist that while it might seem counter-intuitive, the shower is the best option because the tBuLi will react quickly (probably before you even reach the shower) and the large volume of water will suppress the fire and dissipate the heat.

The extent of our systemic ignorance floored me given the relatively high level of news coverage devoted to Sangji’s accident. I realized that while I (personally) have been exposed to a lot of information about the case through paying attention to C&EN and blogs, the majority of people around here seem to know little or nothing about the accident. In spite of the extensive news coverage and publicity, we (as a community) have largely failed to effectively incorporate any “lessons learned” from the accident into our training.

We’ve got a lot of work to do to fix the culture of safety in academia. It’s a shame we never seized the opportunity presented by Sheri Sangji’s death.